Resources

Links to Regulations, Guidelines, and Other Help:

Recombinant DNA Technology

• National Institutes of Health (NIH) Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules
• CDC/United States Department of Agriculture (USDA) Select Agent Program (information and forms)
• National Institutes of Health (NIH) Biosafety Considerations for Research with Lentiviral Vectors
• Stanford University Guidelines for Working with Viral Vectors
• NIH Guidance on Informed Consent For Gene Transfer Research National Institutes of Health Office of Biotechnoloy Activities
• NIH Biosafety Level 3 Certification Requirements

Select Agent

• Laboratory Security and Emergency Response Guidance for Laboratories Working with Select Agents Centers for Disease Control and Prevention
• 32 CFR Part 626 Biological Defense Safety Program
• 32 CFR Part 627 Biological Defense Safety Program, Technical Safety Requirements (DA Pamphlet 385-69)

Microorganism/Virus/Toxin Work

• Risk Group Classification for Infectious Agents American Biological Safety Organization
• Centers for Disease Control and Prevention (CDC) and National Institutes of Health (NIH) Biosafety in Microbiological and Biomedical Labs (full text) (summary)
• Guidelines for Work With Toxins of Biological Origin Centers for Disease Control and Prevention
• Occupational Safety and Health Administration (OSHA) Bloodborne Pathogen Standard (full text) (summary)
• Occupational Safety and Health Administration (OSHA) Occupational Exposure to Hazardous Chemicals in Laboratories Standard (full text) (summary)
• Public Health Agency of Canada Pathogen Safety Data Sheets
• America Society for Microbiolology Large Scale Biosafety Guidelines
• Known Toxin LD50 Values
• Bacterial Toxins: a Table of Lethal Amounts    
•  E. coli K-12 strains

Miscellaneous

• USDA Import and Transport Permits transport permits for organisms "capable of, or is the organism derived from an organism that is capable of introducing or disseminating any contagious or infectious disease of animals (including poultry)"
• Nanoparticle Handling Guidelines
• Laboratory Safety Guidance for Research with SARS-CoV-2 and COVID+ Patient Samples
• Considerations for Handling Potential SARS-CoV-2 Samples